Endocrine Abstracts

Introduction: Low energy trauma fractures are prevalent in end-stage liver disease and after orthotopic liver transplantation (OLT). However, data on bone mineral density (BMD) are scarce in these patients. In this study, we evaluated the natural course of changes in BMD after successful OLT.Study design: All recipients of a successful OLT between 2000 and 2011 from the Leiden University Medical Centre, in whom BMD data were available, were included. Pat...

Introduction: Osteoporosis and fractures are common in liver disease and fracture incidence increases after orthotopic liver transplantation (OLT). The value of bone turnover markers (BMTs) in the prediction of bone loss and fracture risk pre- and post-OLT is not known.Study design: The BMTs P1NP, osteocalcin, BALP and CTX were measured initially or in Biobank stored sera at screening and at 3, 6 and 12 months post-OLT in consecutive OLT recipients betwe...